
Adherent cell expansion.
Simplified.
From lab-scale to large-scale, the CellScrew® helps to overcome scaling bottlenecks in your adherent cell expansion process.

Scale with confidence: reproducible results across all stages.
The transfer from lab to commercial scale is a time and resource intensive process. We help to speed up the scaling process by providing a solution for every step toward accessible therapy.
Available size variants ranging from 850 cm² to 10,000 cm² with comparable process engineering characteristics make it easy for you to scale your cell cultivation process up or down without the need for complex process development.
Less vessels = less work, lower risk, optimized space use
Manual labor drives up to 71% of therapeutic production costs¹. CellScrew® cuts 92% of incubator footprint vs. roller bottles, maximizing cultivation surface area. With a 30% reduction in handling time and less vessels to handle, CellScrew® ensures efficient, high-quality cultivation to prevent batch loss.
Explore our data and application notes to learn about the features in detail.



Archimedes’ screws enable excellent mixing and consistent medium supply under low shear forces
Concentric cyclinders inside the bottle form a large surface area on a small footprint
Central tube empowers constant flow of liquids and allows for liquid handling using a serological pipette
The genius in the bottle
The innovative internal structure of the CellScrew® forms a large growth surface on a small footprint and fosters optimal growth conditions with low shear forces and excellent gas exchange.
Constant and homogeneous supply with oxygen and nutrients facilitate robust cell growth while scaling. Manufacturing from the plant-based material PLA (polylactic acid) this product also comes with a significant reduction in material use and carbon emissions, making the cultivation of cells more sustainable.
Quality by design
Every CellScrew® undergoes rigorous testing to ensure consistency, reliability, and top-quality performance. Quality criteria like ready to use, biocompatibility and full traceability ensure each unit meets strict industry requirements and is suitable to be used in your regulatory setting.


The CellScrew® combines the advantages of other systems for your adherent cell cultivation
Find out how the CellScrew® compares to your current cell cultivation system.
What they both offer:
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growth surface for adherent cells
Why the CellScrew® improves your adherent cell cultivation:
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excellent mixing and gas exchange
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one cultivation vessel with maximized surface
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small footprint efficiently used
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easy handling
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streamlined process

Do you want to know more?
Contact us to learn more, visit our FAQ for the most common questions, or book a demo call to speak to our team to clear any questions and evaluate your options with the CellScrew®.
Talk to our experts!
Book yourself a spot to learn about how the CellScrew® can help you to simplify your cell expansion process.