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3D manufacturing is reshaping life sciences by enabling customized, precise, and scalable solutions. Its adaptability supports innovation in research tools, prototyping, and product development using advanced materials.

Performing fluorescence measurements in the laboratory is a common task and necessary for various assays. Choosing the right equipment for these measurements is essential for the performance of the test. For fluorescence measurements, black well plates are the preferred choice, as they minimize light scattering and reflection of the excitation source.

Well plates are fundamental to the biopharmaceutical industry, but produce a lot of waste by being single-use products. Replacing polystyrene (PS) with polylactic acid (PLA) makes the industry and laboratories more sustainable by reducing carbon emissions up to 50 %.

In cell culture-based biomanufacturing, a seed train refers to the stepwise process of expanding a small number of cells into the large biomass required for production-scale bioreactors. Whether starting from a cryopreserved vial or freshly isolated cells, the seed train builds up sufficient healthy and viable cells for inoculating the final production vessel.

Contamination in cell culture remains one of the most persistent challenges in both research and large-scale bioprocessing. Whether in an academic lab or a GMP-compliant biopharmaceutical facility, contamination can lead to experimental failures, compromised production, and regulatory violations.

The biopharmaceutical manufacturing landscape is undergoing a profound transformation, driven by the rise of personalized therapies, particularly in Cell and Gene Therapeutics. This revolutionary shift is not only redefining the products being developed but also necessitating a complete overhaul of production tools and processes.

Good Manufacturing Practice (GMP) is the foundation of quality assurance in biopharmaceutical manufacturing. It ensures that therapeutic products, including cell therapies and viral vectors like Adeno-Associated Virus (AAV), are produced under strict quality control to meet safety, purity, and efficacy standards.

In cell culture, two primary growth methods exist: adherent culture and suspension culture. The choice between these methods depends on cell type, application, and scalability needs. While adherent cells require attachment to a surface for growth, suspension cells freely float in liquid media. Each approach has its unique advantages, limitations, and specific cultivation requirements.

The successful commercialization of cell and gene therapies (CGTs) depends on the ability to scale production efficiently while maintaining product consistency, safety, and regulatory compliance. A well-designed bioreactor scale-up strategy is critical in ensuring that processes developed in early-stage research can transition seamlessly into commercial-scale biomanufacturing.

The life science tools sector, particularly bioreactor technologies, is emerging as a high-growth investment frontier in Europe, combining scientific innovation with robust market dynamics. Driven by pandemic-era acceleration and sustained demand for biopharmaceuticals, this sector offers compelling opportunities for venture capital (VC) and institutional investors. Here's why bioreactors and related technologies are poised to deliver strong returns while advancing global hea

In the development and manufacture of advanced biopharmaceuticals—including cell and gene therapies—cell expansion is a critical step that directly influences yield, quality, and consistency of the final product. Maintaining a viable and productive cell population requires precise control over multiple parameters within the bioreactor environment. Among these, dissolved oxygen (DO) concentration in the liquid phase stands out as a critical process parameter (CPP).

Bioreactors are essential tools in biotechnology, enabling controlled environments for cell culture, fermentation, and metabolite production. Their role is crucial in biopharmaceutical manufacturing, regenerative medicine, and large-scale cell expansion. As bioprocessing demands grow, bioreactor scale-up becomes a key challenge, ensuring that laboratory-developed processes translate effectively into industrial-scale production.

Scalability is a fundamental challenge in bioprocessing, particularly in cell culture-based manufacturing. As the demand for advanced therapeutics, including cell and gene therapies, continues to grow, manufacturers must choose between two primary strategies for increasing production capacity: scale-up and scale-out.

Cell culture systems are the foundation of modern biopharmaceutical production, playing a crucial role in advanced therapy medicinal products (ATMPs), viral vector manufacturing, and cell-based therapies. The decision between 2D and 3D cell culture impacts scalability, process robustness, and final product quality, making it essential for manufacturers to select the right approach.

In recent years, Germany’s role in biotech has evolved, particularly in cell and gene therapy manufacturing, where its strong GMP expertise is both an asset and a challenge. While Germany remains a key hub for innovation, complex bureaucracy, extensive documentation requirements, and rigid GMP standards have made scaling advanced therapies slow and costly.

Cell and Gene Therapies (CGT) represent a groundbreaking advancement in modern medicine, offering curative potential for genetic disorders, cancer, and degenerative diseases. These therapies utilize engineered cells or genetic modifications to treat or replace damaged tissues and defective genes. All approaches demand highly controlled manufacturing processes to ensure safety, efficacy, and scalability.

Advanced therapies like cell-based therapies have emerged as a promising field in regenerative medicine, offering novel treatment approaches for conditions such as cancer, autoimmune diseases, and degenerative disorders. One critical distinction in these therapies is whether the cells come from the patient themselves (autologous) or from a donor (allogeneic). Both approaches have unique benefits and limitations, impacting their clinical application and scalability.

Sustainability has long been considered a "nice-to-have" in biotech and pharma - but this is changing fast. With the advent of binding regulations like the European Green Deal and its global counterparts, sustainability is moving from corporate responsibility to legal obligation.

Well plates are essential lab tools, available in various sizes and treatments for research, screenings, and cell culture applications.

iPSCs and MSCs are transforming regenerative medicine by curing diseases once considered untreatable.