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Discover the latest insights, industry trends, and expert perspectives. From breakthrough innovations to behind-the-scenes stories, our articles keep you informed and inspired—because great ideas deserve a spotlight!
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The relevance of the oxygen transfer rate for successful cell cultivation
In the development and manufacture of advanced biopharmaceuticals—including cell and gene therapies—cell expansion is a critical step that directly influences yield, quality, and consistency of the final product. Maintaining a viable and productive cell population requires precise control over multiple parameters within the bioreactor environment. Among these, dissolved oxygen (DO) concentration in the liquid phase stands out as a critical process parameter (CPP).
Lukas
46 minutes ago3 min read
2 views


Bioreactors - function, application, and challenges
Bioreactors are essential tools in biotechnology, enabling controlled environments for cell culture, fermentation, and metabolite production. Their role is crucial in biopharmaceutical manufacturing, regenerative medicine, and large-scale cell expansion. As bioprocessing demands grow, bioreactor scale-up becomes a key challenge, ensuring that laboratory-developed processes translate effectively into industrial-scale production.
Mira
4 days ago4 min read
5 views


Scale-up vs. scale-out in bioprocessing
Scalability is a fundamental challenge in bioprocessing, particularly in cell culture-based manufacturing. As the demand for advanced therapeutics, including cell and gene therapies, continues to grow, manufacturers must choose between two primary strategies for increasing production capacity: scale-up and scale-out.
Joel
6 days ago4 min read
5 views


2D vs 3D cell culture: What’s best for scalable biopharmaceutical production?
Cell culture systems are the foundation of modern biopharmaceutical production, playing a crucial role in advanced therapy medicinal products (ATMPs), viral vector manufacturing, and cell-based therapies. The decision between 2D and 3D cell culture impacts scalability, process robustness, and final product quality, making it essential for manufacturers to select the right approach.
Joel
May 94 min read
12 views


Why Germany is falling behind in Cell and Gene Therapeutics (CGT) and how we can turn it around
In recent years, Germany’s role in biotech has evolved, particularly in cell and gene therapy manufacturing, where its strong GMP expertise is both an asset and a challenge. While Germany remains a key hub for innovation, complex bureaucracy, extensive documentation requirements, and rigid GMP standards have made scaling advanced therapies slow and costly.
Felix
May 63 min read
29 views


The base of curing for many diseases: Cell and Gene Therapy Manufacturing
Cell and Gene Therapies (CGT) represent a groundbreaking advancement in modern medicine, offering curative potential for genetic disorders, cancer, and degenerative diseases. These therapies utilize engineered cells or genetic modifications to treat or replace damaged tissues and defective genes. All approaches demand highly controlled manufacturing processes to ensure safety, efficacy, and scalability.
Mira
Apr 285 min read
20 views


Autologous vs allogenic cell therapy: key differences and applications
Advanced therapies like cell-based therapies have emerged as a promising field in regenerative medicine, offering novel treatment approaches for conditions such as cancer, autoimmune diseases, and degenerative disorders. One critical distinction in these therapies is whether the cells come from the patient themselves (autologous) or from a donor (allogeneic). Both approaches have unique benefits and limitations, impacting their clinical application and scalability.
Katharina
Apr 255 min read
33 views


Mandatory sustainability: How the Green Deal and Global Regulations are reshaping biotech
Sustainability has long been considered a "nice-to-have" in biotech and pharma - but this is changing fast. With the advent of binding regulations like the European Green Deal and its global counterparts, sustainability is moving from corporate responsibility to legal obligation.
Mira
Apr 168 min read
18 views


Well plates: sizes, variants and their application in the lab
Well plates are essential lab tools, available in various sizes and treatments for research, screenings, and cell culture applications.
Annika
Apr 74 min read
11 views


iPSC and MSCs: Transforming Regenerative Medicine
iPSCs and MSCs are transforming regenerative medicine by curing diseases once considered untreatable.
Katharina
Apr 35 min read
24 views


What are iPSCs and MSCs and how are stem cells cultivated?
Stem cell cultivation of iPSCs and MSCs is essential to ensure scalability for regenerative medicine and advanced therapies.
Katharina
Mar 314 min read
13 views


Working together for a sustainable future: Bürkert Fluid Control Systems and Green Elephant Biotech
Working together for a sustainable future: Bürkert Fluid Control Systems and Green Elephant Biotech
Mira
Feb 134 min read
178 views


New addition to innovative CellScrew® product line: a down-scale model for adherent cell culture
Green Elephant adds a new member to CellScrew® series: CellScrew® mini as an entry-level solution for efficient, scalable cell culture
Mira
Jul 8, 20242 min read
140 views


Green Elephant Biotech expands sustainable 96-well plate line for light-sensitive experiments
Green Elephant Biotech is expanding its product line of plant-based 96-well plates with two new additions: black and white 96-well plates.
Mira
Apr 9, 20242 min read
94 views


The complex problem behind sustainability in the life and health sciences sector
4.4% of the global net emissions are produced by the healthcare sector. What does it need for the sector to become more sustainable?
Josephine Greenall-Ota, Mira Sternstein
Mar 27, 20249 min read
207 views


CellScrew® Expert Series
Welcome to this special blog post, a short video series, created to enhance your workflow and steer clear of potential pitfalls! Whether...
Carolin
Feb 6, 20242 min read
191 views


Product launch: Green Elephant Biotech launches the world's first plant-based 96-well plate
News: Green Elephant Biotech launches the world's first plant-based 96-well plate
Carolin
Jan 29, 20242 min read
113 views


Efficiently manufacturing high-quality cell and gene therapies
What makes a good adherent cell expansion system for cell and gene therapy? There is a great need for adherent cell expansion systems...
Josephine Greenall-Ota
Dec 14, 20238 min read
420 views


Why we need adherent cell culture expansion systems.
Aren't suspension systems good enough? Adherent cells are the backbone of recent biotechnology innovations that work towards a...
Josephine Greenall-Ota
Sep 28, 20239 min read
388 views


The bottleneck that keeps patients waiting for access to affordable advanced therapies
The bioprocessing industry’s manufacturing capacity crunch Imagine a world where chronic diseases such as heart diseases, cancers, or...
Josephine Greenall-Ota
Aug 25, 202310 min read
427 views

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