The surface area that fits your cell cultivation needs
Stop operating with a multitude of cell culture vessels to achieve a large growth area. The CellScrew® covers up to 10,000 cm², allowing you to grow adherent cells in a compact vessel without the need for numerous or bulky vessels.
Applications
Cell therapies
Vaccine manufacturing
Seed train
Viral vector production
Less vessels = reduced work load
Optimize your cell cultivation process with a surface area fulfilling your needs. Minimize manual labor, space requirements, contamination risks associated with handling numerous vessels and ultimately reduce your cultivation costs.
Scale with confidence: reproducible results across all stages.
Available size variants ranging from 850 cm² to 10,000 cm² with comparable process engineering characteristics make it easy for you to scale your cell cultivation process up or down without the need for a complex process development.
The genius in the bottle
The innovative internal structure of the CellScrew® forms a large growth surface on a small footprint and fosters optimal growth conditions with low shear forces and excellent gas exchange.
Constant and homogeneous supply with oxygen and nutrients facilitate cell growth while limiting unwanted cell differentiation.
Internal Archimedes’ screws enable excellent mixing and consistent medium supply under low shear forces
The central tube empowers constant flow of the liquids and allows for liquid handling using a serological pipette.
Concentric cyclinders inside the bottle form a large surface area on a small footprint
Efficiently use available incubator space
The CellScrew® provides an extensive growth area within a compact footprint, efficiently making use of available incubator space and reducing the vessels needed per batch.
Resource-conscious cell cultivation
The CellScrew® not only conserves your resources but also those of our planet. Through material-efficient additive manufacturing and the use of plant-based materials, the CellScrew® boasts a 90% lower carbon footprint than other adherent cell cultivation systems.
CellScrew®
Common systems
The CellScrew® combines the advantages of other systems for your adherent cell cultivation
Find out how the CellScrew® compares to your cell cultivation system.
What they both offer:
Why the CellScrew® improves your adherent cell cultivation:
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growth surface for adherent cells
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excellent mixing and gas exchange
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one cultivation vessel with maximized surface
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small footprint efficiently used
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easy handling
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streamlined process
Model | Coming soon: CellScrew® mini | CellScrew® 6K | CellScrew® 10K |
---|---|---|---|
Growth area | 850 cm² | 6,000 cm² | 10,000 cm² |
Media volume | 50 - 120 mL | 250 - 800 mL | 450 - 1,300 mL |
Recommended media volume | 85 mL | 600 mL | 1,000 mL |
Height | 16.78 cm | 19.19 cm | 28.39 cm |
Diameter | 5.3 cm | 12.1 cm | 12.1 cm |
Weight | 120 g | 550 g | 860 g |
Recommended speed | 0.2 to 2 rpm | 0.2 to 2 rpm | 0.2 to 2 rpm |
Mixing times (@ 0.5 rpm) | < 8 min | < 9 min | < 27 min |
kLA (@0.5 rpm) | N/A | 1.95 h-1 | 1.95 h-1 |
Sterilization | sterile (gamma irradiated), not autoclavable | sterile (gamma irradiated), not autoclavable | sterile (gamma irradiated), not autoclavable |
Material | PLA (polylactic acid), TC-treated | PLA (polylactic acid), TC-treated | PLA (polylactic acid), TC-treated |
Coming soon.