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The CellScrew®

Scaling adherent cell yields in minimal space

Facilitate your adherent cell cultivation process:

  • small footprint, large growth surface

  • seamless up and down scaling

  • sustainable, plant-based design

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The surface area that fits your cell cultivation needs

Stop operating with a multitude of cell culture vessels to achieve a large growth area. The CellScrew® covers up to 10,000 cm², allowing you to grow adherent cells in a compact vessel without the need for numerous or bulky vessels.

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Applications

Cell therapies

Vaccine manufacturing

Seed train

Viral vector production

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Less vessels = reduced work load

Optimize your cell cultivation process with a surface area fulfilling your needs. Minimize manual labor, space requirements, contamination risks associated with handling numerous vessels and ultimately reduce your cultivation costs.

Scale with confidence: reproducible results across all stages.

Available size variants ranging from 850 cm² to 10,000 cm² with comparable process engineering characteristics make it easy for you to scale your cell cultivation process up or down without the need for a complex process development. 

The genius in the bottle

The innovative internal structure of the CellScrew® forms a large growth surface on a small footprint and fosters optimal growth conditions with low shear forces and excellent gas exchange.

Constant and homogeneous supply with oxygen and nutrients facilitate cell growth while limiting unwanted cell differentiation.

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Internal Archimedes’ screws enable excellent mixing and consistent medium supply under low shear forces

The central tube empowers constant flow of the liquids and allows for liquid handling using a serological pipette.

Concentric cyclinders inside the bottle form a large surface area on a small footprint

Efficiently use available incubator space

The CellScrew® provides an extensive growth area within a compact footprint, efficiently making use of available incubator space and reducing the vessels needed per batch.

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Resource-conscious cell cultivation

The CellScrew® not only conserves your resources but also those of our planet. Through material-efficient additive manufacturing and the use of plant-based materials, the CellScrew® boasts a 90% lower carbon footprint than other adherent cell cultivation systems. 

CellScrew®

Common systems

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The CellScrew® combines the advantages of other systems for your adherent cell cultivation

Find out how the CellScrew® compares to your cell cultivation system.

What they both offer: 

Why the CellScrew® improves your adherent cell cultivation:

  • growth surface for adherent cells

  • excellent mixing and gas exchange

  • one cultivation vessel with maximized surface

  • small footprint efficiently used

  • easy handling

  • streamlined process

Model
Coming soon: CellScrew® mini
CellScrew® 6K
CellScrew® 10K
Growth area
850 cm²
6,000 cm²
10,000 cm²
Media volume
50 - 120 mL
250 - 800 mL
450 - 1,300 mL
Recommended media volume
85 mL
600 mL
1,000 mL
Height
16.78 cm
19.19 cm
28.39 cm
Diameter
5.3 cm
12.1 cm
12.1 cm
Weight
120 g
550 g
860 g
Recommended speed
0.2 to 2 rpm
0.2 to 2 rpm
0.2 to 2 rpm
Mixing times (@ 0.5 rpm)
< 8 min
< 9 min
< 27 min
kLA (@0.5 rpm)
N/A
1.95 h-1
1.95 h-1
Sterilization
sterile (gamma irradiated), not autoclavable
sterile (gamma irradiated), not autoclavable
sterile (gamma irradiated), not autoclavable
Material
PLA (polylactic acid), TC-treated
PLA (polylactic acid), TC-treated
PLA (polylactic acid), TC-treated

Coming soon. 

Start cultivating efficiently and sustainably with our starter-bundle.

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Order 3 CellScrew® 6K with a bundle discount

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Receive detailed onboarding from our Sales team

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Get expert support from our R&D team

Do you want to know more? 
Book a free intro call. 

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